Circulation
This guideline updates the recommendations on anticoagulation, catheter ablation of atrial fibrillation (AF), management of AF complicating acute coronary syndrome, and includes new recommendations on device detection of AF and weight loss.
National Institute for Health Research Signal
Expert commentary is provided for a review of 16 RCTs (n=22,396) which found that all oral anticoagulants regimens reduce the risk of recurrent VTE vs placebo. Ideal regimens for those at higher risk (e.g. thrombophilia), and >1 year treatment still require further investigation.
Additional GI bleeding risk with SSRIs in people with declining kidney function: DTB Select
Drug and Therapeutics Bulletin
Summary and context is provided for a cohort study which reported an increased risk of GI bleeding with SSRIs in patients with CKD. Clinicians are advised to review the risks and benefits of SSRIs in this population and consider the need for gastroprotection.
The above records have been identified by UKMi and feature in the NICE Medicines Awareness Service. Further details on this service can be found at:
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