Saturday, 06 November 2021 13:25

Anticoagulation news items. Week commencing 1st November 2021

Oral Anticoagulant Use in Patients with Morbid Obesity: A Systematic Review and Meta-Analysis

Journal of Thrombosis and Haemastasis
Review of 3 RCTs and 18 observational studies in morbidly obese found those on DOACs had lower rates of recurrent VTE than those on vitamin K antagonists (3.83 vs 6.81 per 100 person years). Rates of stroke and systemic embolism and major bleeding events were similar.

 

Using oral anticoagulants in breastfeeding women

Specialist Pharmacy Service
Evidence summary notes thromboembolic disease management whilst breastfeeding is challenging. Warfarin is the preferred choice, but guidance on using DOACs is also provided. It notes recommendations apply to full-term and healthy infants only.

 

The above records have been identified by UKMi and feature in the NICE Medicines Awareness Service. Further details on this service can be found at:

http://www.evidence.nhs.uk/about-evidence-services/content-and-sources/medicines-information/new-medicines-awareness-services