Sunday, 17 July 2022 18:44

Anticoagulation news items. Week commencing 11th July 2022

Intranasal Topical Application of Tranexamic Acid in Atraumatic Anterior Epistaxis: A Double-Blind Randomized Clinical Trial

Annals of Emergency Medicine
RCT (n=240) found addition of tranexamic acid to controlled therapy of phenylephrine & lidocaine was linked to a lower rate of need for anterior nasal packing (50% vs 64.2%; OR 0.56; 95% CI 0.33-0.94), stay in A+E for >2hrs (9.2% vs 20.8%) & rebleeding in 24hrs (15% vs 30%).

 

 

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